CONDENSED CONSOLIDATED STATEMENT OF CHANGES IN EQUITY - USD ($) |
Series D Preferred Stock [Member]
Common Stock [Member]
At-the-market Offering [Member]
|
Series D Preferred Stock [Member]
Common Stock [Member]
Exercise of Warrants [Member]
|
Series D Preferred Stock [Member]
Common Stock [Member]
|
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
At-the-market Offering [Member]
|
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
Exercise of Warrants [Member]
|
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
|
Series E Preferred Stock [Member]
Retained Earnings [Member]
|
Series C Preferred Stock [Member]
Common Stock [Member]
Settlement of Preferred Stock [Member]
|
Series C Preferred Stock [Member]
Common Stock [Member]
|
Series C Preferred Stock [Member]
Additional Paid-in Capital [Member]
Settlement of Preferred Stock [Member]
|
Series C Preferred Stock [Member]
Additional Paid-in Capital [Member]
|
Series C Preferred Stock [Member]
Settlement of Preferred Stock [Member]
|
Series C Preferred Stock [Member] |
Common Stock [Member]
At-the-market Offering [Member]
|
Common Stock [Member]
Exercise of Warrants [Member]
|
Common Stock [Member]
Cashless Exercise of Warrants [Member]
|
Common Stock [Member]
Cashless Exercise of Options [Member]
|
Common Stock [Member] |
Additional Paid-in Capital [Member]
Trek Therapeutics [Member]
|
Additional Paid-in Capital [Member]
At-the-market Offering [Member]
|
Additional Paid-in Capital [Member]
Exercise of Warrants [Member]
|
Additional Paid-in Capital [Member]
Cashless Exercise of Warrants [Member]
|
Additional Paid-in Capital [Member]
Cashless Exercise of Options [Member]
|
Additional Paid-in Capital [Member] |
Retained Earnings [Member] |
Noncontrolling Interest [Member]
Trek Therapeutics [Member]
|
Noncontrolling Interest [Member] |
Receivables from Stockholder [Member]
Subscription Arrangement [Member]
|
Receivables from Stockholder [Member] |
Trek Therapeutics [Member] |
At-the-market Offering [Member] |
Exercise of Warrants [Member] |
Subscription Arrangement [Member] |
Cashless Exercise of Options [Member] |
Total |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Balance at Dec. 31, 2018 | $ 16,869 | $ 74,039,341 | $ (70,731,941) | $ 3,324,269 | |||||||||||||||||||||||||||||||
Balance (in Shares) at Dec. 31, 2018 | 16,868,783 | ||||||||||||||||||||||||||||||||||
Sale of common stock | $ 2,155 | 8,617,123 | 8,619,278 | ||||||||||||||||||||||||||||||||
Sale of common stock (in Shares) | 2,155,127 | ||||||||||||||||||||||||||||||||||
Common stock issued for services | $ 973 | 5,802,455 | 5,803,428 | ||||||||||||||||||||||||||||||||
Common stock issued for services (in Shares) | 973,317 | ||||||||||||||||||||||||||||||||||
Common stock issued upon conversion of preferred stock and accrued dividends | $ 21 | $ 69 | $ 139,571 | $ 259,931 | $ 139,592 | $ 260,000 | |||||||||||||||||||||||||||||
Common stock issued upon conversion of preferred stock and accrued dividends (in Shares) | 21,379 | 69,335 | |||||||||||||||||||||||||||||||||
Sale of subsidiary shares to non-controlling interest | 3,268,434 | $ 426,212 | $ 501,000 | $ 501,000 | 3,694,646 | ||||||||||||||||||||||||||||||
Change in fair value of modified options | 666,062 | 666,062 | |||||||||||||||||||||||||||||||||
Common stock issued upon exercise of options | $ 39 | $ 98 | $ (39) | 465,100 | 465,198 | ||||||||||||||||||||||||||||||
Common stock issued upon exercise of options (in Shares) | 38,687 | 97,500 | |||||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants | $ 1,563 | $ 162 | $ 6,353,307 | $ (162) | $ 6,354,870 | ||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants (in Shares) | 1,562,896 | 161,986 | |||||||||||||||||||||||||||||||||
Stock based compensation | $ 83 | 1,892,775 | 1,892,858 | ||||||||||||||||||||||||||||||||
Stock based compensation (in Shares) | 83,332 | ||||||||||||||||||||||||||||||||||
Preferred Stock dividend | (20,286) | (20,286) | |||||||||||||||||||||||||||||||||
Net loss | (19,262,618) | (20,538) | (19,283,156) | ||||||||||||||||||||||||||||||||
Balance at Sep. 30, 2019 | $ 22,032 | 101,483,612 | (89,994,559) | 405,674 | $ 501,000 | 12,417,759 | |||||||||||||||||||||||||||||
Balance (in Shares) at Sep. 30, 2019 | 22,032,342 | ||||||||||||||||||||||||||||||||||
Balance at Jun. 30, 2019 | $ 21,151 | 94,494,972 | (84,551,093) | 9,965,030 | |||||||||||||||||||||||||||||||
Balance (in Shares) at Jun. 30, 2019 | 21,151,134 | ||||||||||||||||||||||||||||||||||
Common stock issued for services | $ 413 | 1,196,215 | 1,196,628 | ||||||||||||||||||||||||||||||||
Common stock issued for services (in Shares) | 413,317 | ||||||||||||||||||||||||||||||||||
Sale of subsidiary shares to non-controlling interest | 3,268,434 | 426,212 | $ 501,000 | $ 501,000 | 3,694,646 | ||||||||||||||||||||||||||||||
Common stock issued upon exercise of options | $ 4 | 20,356 | 20,360 | ||||||||||||||||||||||||||||||||
Common stock issued upon exercise of options (in Shares) | 4,000 | ||||||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants | $ 433 | $ 1 | 1,735,950 | (1) | 1,736,383 | ||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants (in Shares) | 432,867 | 1,024 | |||||||||||||||||||||||||||||||||
Stock based compensation | $ 30 | 772,563 | 772,593 | ||||||||||||||||||||||||||||||||
Stock based compensation (in Shares) | 30,000 | ||||||||||||||||||||||||||||||||||
Preferred Stock dividend | (4,877) | (4,877) | |||||||||||||||||||||||||||||||||
Net loss | (5,443,466) | (20,538) | (5,464,004) | ||||||||||||||||||||||||||||||||
Balance at Sep. 30, 2019 | $ 22,032 | 101,483,612 | (89,994,559) | 405,674 | $ 501,000 | 12,417,759 | |||||||||||||||||||||||||||||
Balance (in Shares) at Sep. 30, 2019 | 22,032,342 | ||||||||||||||||||||||||||||||||||
Balance at Dec. 31, 2019 | $ 23,323 | 115,910,058 | (104,786,769) | 514,828 | $ 11,661,440 | ||||||||||||||||||||||||||||||
Balance (in Shares) at Dec. 31, 2019 | 23,323,087 | 23,323,087 | |||||||||||||||||||||||||||||||||
Sale of common stock | $ 150 | $ 4,688 | $ 1,001,613 | 25,209,623 | $ 1,001,763 | $ 25,214,311 | |||||||||||||||||||||||||||||
Sale of common stock (in Shares) | 150,000 | 4,687,500 | |||||||||||||||||||||||||||||||||
Common stock issued for services | $ 503 | 3,550,401 | $ 3,550,904 | ||||||||||||||||||||||||||||||||
Common stock issued for services (in Shares) | 503,038 | 503,038 | |||||||||||||||||||||||||||||||||
Fair value of subsidiary shares issued to acquire research and development | $ 2,439,139 | 1,051,309 | $ 735,411 | 248,486 | $ 3,174,550 | $ 1,299,795 | |||||||||||||||||||||||||||||
Common stock issued upon conversion of preferred stock and accrued dividends | $ 16 | $ 29 | $ 70,325 | $ 109,971 | $ 70,341 | $ 110,000 | |||||||||||||||||||||||||||||
Common stock issued upon conversion of preferred stock and accrued dividends (in Shares) | 15,516 | 29,334 | |||||||||||||||||||||||||||||||||
Sale of subsidiary shares to non-controlling interest | 7,124,366 | $ 983,897 | 3,467,709 | 10,592,075 | |||||||||||||||||||||||||||||||
Common stock issued upon exercise of options | $ 161 | $ 586 | $ (161) | 2,721,426 | $ 2,722,012 | ||||||||||||||||||||||||||||||
Common stock issued upon exercise of options (in Shares) | 160,743 | 586,825 | 616,398 | 1,203,223 | |||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants | $ 430 | $ 13 | $ 1,666,065 | $ (13) | 1,666,495 | ||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants (in Shares) | 429,979 | 12,840 | |||||||||||||||||||||||||||||||||
Stock based compensation | $ 219 | 14,385,910 | 2,636,298 | $ 17,022,427 | |||||||||||||||||||||||||||||||
Stock based compensation (in Shares) | 219,334 | ||||||||||||||||||||||||||||||||||
Preferred Stock dividend | (11,698) | (11,698) | |||||||||||||||||||||||||||||||||
Net loss | (41,925,704) | (6,282,420) | (48,208,124) | ||||||||||||||||||||||||||||||||
Balance at Sep. 30, 2020 | $ 30,118 | $ 175,228,334 | $ (146,712,473) | $ 30,118 | 175,228,334 | (146,712,473) | 1,320,312 | $ 29,866,291 | |||||||||||||||||||||||||||
Balance (in Shares) at Sep. 30, 2020 | 30,118,196 | 30,118,196 | 30,118,196 | ||||||||||||||||||||||||||||||||
Balance at Jun. 30, 2020 | $ 29,127 | 168,499,417 | (135,310,614) | 2,793,950 | $ 36,011,880 | ||||||||||||||||||||||||||||||
Balance (in Shares) at Jun. 30, 2020 | 29,126,663 | ||||||||||||||||||||||||||||||||||
Sale of common stock | $ 150 | $ 1,001,613 | $ 1,001,763 | ||||||||||||||||||||||||||||||||
Sale of common stock (in Shares) | 150,000 | ||||||||||||||||||||||||||||||||||
Common stock issued for services | $ 488 | 3,442,142 | 3,442,630 | ||||||||||||||||||||||||||||||||
Common stock issued for services (in Shares) | 488,000 | ||||||||||||||||||||||||||||||||||
Common stock issued upon exercise of options | $ 108 | 492,424 | 492,532 | ||||||||||||||||||||||||||||||||
Common stock issued upon exercise of options (in Shares) | 108,374 | ||||||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants | $ 160 | $ 632,039 | $ 632,199 | ||||||||||||||||||||||||||||||||
Common stock issued upon exercise of warrants (in Shares) | 160,159 | ||||||||||||||||||||||||||||||||||
Stock based compensation | $ 85 | 1,163,080 | 222,944 | 1,386,109 | |||||||||||||||||||||||||||||||
Stock based compensation (in Shares) | 85,000 | ||||||||||||||||||||||||||||||||||
Preferred Stock dividend | (2,381) | (2,381) | |||||||||||||||||||||||||||||||||
Net loss | (11,401,859) | (1,696,582) | (13,098,441) | ||||||||||||||||||||||||||||||||
Balance at Sep. 30, 2020 | $ 30,118 | $ 175,228,334 | $ (146,712,473) | $ 30,118 | $ 175,228,334 | $ (146,712,473) | $ 1,320,312 | $ 29,866,291 | |||||||||||||||||||||||||||
Balance (in Shares) at Sep. 30, 2020 | 30,118,196 | 30,118,196 | 30,118,196 |