Quarterly report pursuant to Section 13 or 15(d)

CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY (DEFICIT)

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CONDENSED CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY (DEFICIT) - USD ($)
$ in Thousands
At-the-Market Offering [Member]
Series D Preferred Stock [Member]
Common Stock [Member]
At-the-Market Offering [Member]
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
At-the-Market Offering [Member]
Settlement of Preferred Stock [Member]
Series D Preferred Stock [Member]
Common Stock [Member]
Settlement of Preferred Stock [Member]
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
Settlement of Preferred Stock [Member]
Series C Preferred Stock [Member]
Cashless Exercise of Warrants [Member]
Series D Preferred Stock [Member]
Common Stock [Member]
Exercise of Warrants [Member]
Series D Preferred Stock [Member]
Common Stock [Member]
Exercise of Warrants [Member]
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
Exercise of Warrants [Member]
Trek Therapeutics, PBC [Member]
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
Trek Therapeutics, PBC [Member]
Noncontrolling Interest [Member]
Trek Therapeutics, PBC [Member]
Series D Preferred Stock [Member]
Common Stock [Member]
Series E Preferred Stock [Member]
Additional Paid-in Capital [Member]
Series E Preferred Stock [Member]
Retained Earnings [Member]
Series C Preferred Stock [Member]
Noncontrolling Interest [Member]
Total
Balance at Dec. 31, 2019                           $ 23 $ 115,910 $ (104,787)   $ 515 $ 11,661
Balance (in Shares) at Dec. 31, 2019                           23,323,087          
Common stock issued upon exercise of options (in Shares)                           11,141          
Sale of common stock                           $ 2 9,050       9,052
Sale of common stock (in Shares)                           2,500,000          
Common stock issued upon conversion of preferred stock and accrued dividends         $ 6 $ 6                 10   $ 10    
Common stock issued upon conversion of preferred stock and accrued dividends (in Shares)       1,083                   2,667          
Common stock issued upon exercise of warrants               $ 1 $ 301 $ 302                  
Common stock issued upon exercise of warrants (in Shares)             10,574 80,432                      
Fair value of subsidiary shares issued to acquire research and development                     $ 2,440 $ 735 $ 3,175            
Stock based compensation                             3,628     785 4,413
Stock based compensation (in Shares)                           81,334          
Preferred Stock dividend                             (5)       (5)
Net loss                               (11,335)   (1,428) (12,763)
Balance at Mar. 31, 2020                           $ 26 131,340 (116,122)   607 15,851
Balance (in Shares) at Mar. 31, 2020                           26,010,318          
Balance at Dec. 31, 2020                           $ 31 181,344 (157,005)   802 $ 25,172
Balance (in Shares) at Dec. 31, 2020                           30,764,792         30,764,792
Common stock issued for services                             1,777       $ 1,777
Common stock issued for services (in Shares)                           406,692         406,692
Common stock issued upon exercise of options                             28       $ 28
Common stock issued upon exercise of options (in Shares)                           9,375         9,375
Sale of common stock   $ 1,300 $ 1,300                                
Sale of common stock (in Shares) 251,720                                    
Stock based compensation                           $ 1 721     20 $ 742
Stock based compensation (in Shares)                           682,202          
Preferred Stock dividend                             (2)       (2)
Net loss                               (8,319)   (240) (8,559)
Balance at Mar. 31, 2021                           $ 32 $ 185,168 $ (165,324)   $ 582 $ 20,458
Balance (in Shares) at Mar. 31, 2021                           32,114,781         32,114,781